School of Pharmacy
Medical Sciences Campus
University of Puerto Rico
PO Box 365067
San Juan, PR 00936-5067
Tel. (787) 758-2525 ext. 5413
Fax. (787) 767-2796
Academic Training:
Post-Doctoral in Chemistry, Medical University of South Carolina, South Carolina (1992)
Ph.D. in Chemistry, University of Puerto Rico, Río Piedras Campus (1991)
B.S. in Chemistry (Cum Laude), University of Puerto Rico, Río Piedras Campus (1985)
Professional Experience: Academic
2000 to date Associate Professor Pharmaceutical Science Department, School of Pharmacy, Medical Sciences Campus, University of Puerto Rico
1995 to 2000 Assistant Professor, Pharmaceutical Science Department, School of Pharmacy, Medical Sciences Campus, University of Puerto Rico
1994 Instructor, Analytical Chemistry Laboratory, University of Puerto Rico
1989 Chemistry Professor and Laboratory Instructor~ Metropolitan University, Cupey, Puerto Rico
1989 Chemistry Teacher for high school students in the C.A.U.S.A. Program, Metropolitan University, Cupey, Puerto Rico
1988 Chemistry Teacher for high school students in the C.A.U.S.A. Program, Metropolitan University, Cupey, Puerto Rico
Administrative:
2011- to date Assistant Dean of Research and the Graduate Program at the School of Pharmacy, University of Puerto Rico
2006 –to 2009 Crime Laboratory Director at the Forensic Science Institute of Puerto Rico
2005 -2006 Acting Assistant Dean of the Graduate Program at the School of Pharmacy, University of Puerto Rico
1995 to 1998 Associate Director, Doping Control and Chemical Analysis Laboratory (Toxicology), Medical Sciences Campus, University of Puerto Rico
1993-1995 Technical Associate Director, Doping Control and Chemical Analysis Laboratory (Toxicology), Medical Sciences Campus, University of Puerto Rico
Professional Activities:
2006 Course “Desarrollo y Validación de Métodos Cromatográficos para el Análisis de Productos Farmacéuticos y Suplementos Dietéticos, Universidad Del Valle, Guatemala
2005 Course “Desarrollo y Validación de Métodos Cromatográficos para el Análisis de Productos Farmacéuticos y Suplementos Dietéticos, Universidad Del Valle, Guatemala
2004 Course “Práctica de Bioquímica Clínica del Programa de Maestría en Ciencias de Laboratorio, University of Puerto Rico, Medical Sciences Campus
2004 Course “Introduction of HPLC”, at the Puerto Rico Health Department, Tuberculosis Division
2004 Course “GC/MS Principles and Applications” at the Forensic Science Institute in Puerto Rico
2004 Course on Good Laboratory Practices and General Aspects of Validation in Analytical Methodology, I Congreso de Ciencias Farmacéuticas de la Conferencia Hispanoamericana de Facultades de Farmacia, Guatemala
2004 Course “Principios y Aplicaciones de Cromatografía Líquida y Gas”, Programa Educación Continua para Tecnólogos Médicos
2003 Course “Cromatografía Líquida Acoplada a Espectrometría de Masas: Principios y Aplicaciones, Programa Educación Continua, Colegio de Químicos
2003 Course on Instrumental Analysis for the Doctoral Program at the Public Health School, Medical Sciences Campus
2003 Course “Práctica de Bioquímica Clínica del Programa de Maestría en Ciencias de Laboratorio, University of Puerto Rico, Medical Sciences Campus
2002 Training in Sample Preparation and Analysis, Protocol Development and Interpretation of Results by Mass Spectrometry for the Legal Medicine Institute of the Supreme Court of Nicaragua
2002 Course on Mass Spectrometry and Practical Laboratory Experiences for the Legal Medicine Institute of the Supreme Court of Nicaragua
2001 Course “Monitoreo de Medicamentos y Toxicología Clínica del Programa de Maestría en Ciencias de Laboratorio, University of Puerto Rico, Medical Sciences Campus
2001 Course on Analytical Techniques used in Different Areas of Chemistry, 60ma Conferencia y Convención Anual de Químicos, Río Grande Puerto Rico
2000 Course on Gas Chromatography/Mass Spectrometry and Practical Laboratory Experiences for the Public Ministry in Guatemala, Guatemala City
2000 Course on Capillary Electrophoresis, Programa Educación Continua, Colegio de Químicos
2000 Course on Mass Spectrometry Fundamentals and Applications, 60ma Conferencia y Convención Anual de Químicos, Rio Grande Puerto Rico
2001 Course on Instrumental Analysis for the Doctoral Program at the Public Health School, Medical Sciences Campus
1998 Course in Advance Biochemistry for the Masters Program of Clinical Laboratory at the College of Health Allied Professions, Medical Sciences Campus
1997 Coordinator of Therapeutic Drug Monitoring in Clinical Laboratory Sciences at the
College of Allied Health Professions, Medical Sciences Campus, at the graduate level (Clinical Biochemistry)
1997 Integrated Instrumental Analysis Techniques utilized in the clinical laboratory, Clinical Laboratory Sciences at the College of Allied Health Professions, Medical Sciences Campus, at the graduate level. Integrated laboratory experiences
1995 Taught a graduate course in Biochemical and Biomedical Analysis of Drug using different analytical techniques at the School of Pharmacy, Medical Sciences Campus, University of Puerto Rico
1994 Instructor for different techniques of Mass Spectrometry in the Analysis of Drug at the School of Pharmacy, School of Pharmacy, Medical Sciences Campus, University of Puerto Rico
Committees:
• Member of theAdvisory Committee on Pharmaceutical Sciences of the Food and Drug Administration (FDA) (1999 – 2003)
• Member of the Personnel Committee- Representative to Faculty Personnel Committee (2004-2005)
• Member of the Graduate Committee (President 2004-2005)
• Member of the Students and Faculty Committee (2004-2005)
• Member of the Institutional Biosafety Committee (2000 – present)
• Member of the Faculty Representative Committee (2003-2005)
• Faculty Representative at Staff Meetings (2001-2005)
• Member of the Advisor Committee for the RISE Program (2006)
Research:
1998-present Research Associate at the Center for Environmental and Toxicological Research Medical Sciences Campus, University of Puerto Rico
1992-1993 Research Fellow, Department of Pharmacology, Medical University of South Carolina, Charleston, South Carolina
1991-1992 Research Scientist, National Center for Toxicological Research (NCTR) under the Commissioned Officer for Student Training and Exchange Program (COSTEP)
1990 -1991 Research Scientist at NCTR in the mass spectrometry laboratory in the Division of Biochemical Toxicology under the COSTEP Program
1985-1989 Research and Teaching Assistantship, University of Puerto Rico
Honors and Awards:
• BS degree in Chemistry with honors (Cum Laude) (1985)
• Commissioned Officer Student Training Exchange Program (1989-91) Ford Foundation Post-doctoral Fellowship (1992-93)
• RCMI Travel Award to National Cancer Institute (1996, 2004)
• National Hispanic Conference in San Antonio, Texas International Who’s Who Organization
• Rho Chi Society
• Premio al mejor diseño de Proyecto Individual, Proyecto Atlantea “Desarrollo y Validación de Metodología Analítica para Establecer Protocolos de Suplementos Dietéticos”
• 2nd prize in the category of Major Academic Impact Projects at the Proyecto Atlantea 8va Jornada de Estudios Caribeños, Universidad de Puerto Rico, Recinto de Río Piedras, March 2006
• FDA Group Recognition Award as a member of the “Compounding Pharmacy Survey Team”
Attendance at Professional and Scientific Meetings:
• XXVI Foro Anual de Investigación y Educación, University of Puerto Rico, Medical Sciences Campus, April (2006)
• Proyecto Atlantea 8va Jornada de Estudios Caribeños, Universidad de Puerto Rico, Recinto de Río Piedras, March 2006
• 1st internacional Congreso of Analytical Chemistry Applied, Lima, Perú, September (2005)
• 64ta Conferencia y Convención Anual del Colegio de Químicos de Puerto Rico, San Juan, Puerto Rico, Agosto (2005)
• Excipient Fest 2005 – Technical Conference, Mutchler Inc., San Juan, Puerto Rico (2005)
• XXV Foro Anual de Investigación y Educación, University of Puerto Rico, Medical Sciences Campus, March (2005)
• 28th Annual Pharmaceutical Technical Conference, Puerto Rico Pharmaceutical Quality Association, San Juan, Puerto Rico, January (2005)
• 14ta Conferencial Anual Autogestión en la Protección y Defensa de los Derechos de las personas con Impedimentos, December 2004
• Excipientfest 2004 Technical Conference & Trade Expo, San Juan, Puerto Rico, (2004) XXIV Foro Anual de Investigación y Educación, University of Puerto Rico, Medical Sciences Campus, March (2004)
• VII Asamblea General de la Conferencia Hispanoamericana de Facultades de Farmacia, Ciudad de Guatemala, Guatemala, Abril (2004)
• 2nd Symposium on Ethics & Integrity in Science & Research, San Juan, Puerto Rico, November 20, 2003
• Forum for Innovation in Pharmaceutical and Packaging Technologies, Dorado, Puerto Rico, May 2001
• NSF Industry/University Cooperative Research Center in Pharmaceutical Processing, Dorado, Puerto Rico, May 9-11, 2001
• 60ma Conferencia y Convención Anual de Químicos, Río Grande Puerto Rico, Agosto 2001
• 25th Annual International Symposium on Environmental Analytical Chemistry, Geneva, Switzerland, (1998)
• Society of Environmental Toxicology and Chemistry 1st Annual Meeting, San Francisco, California (1997)
• 2nd Annual International Symposium on Environmental Analytical Chemistry, Jekyll Island, Georgia (1997) Fifth RCMI International AIDS Symposium, Rio Grande, Puerto Rico (1996)
• American Society for Mass Spectrometry Conference, Atlanta, Georgia (1995)
• Worked as a judge at the “Feria Cientifica Nacional”, Caguas, Puerto Rico (1995)
• Society Organization for Forensic Toxicology Conference in Drug Testing for Hair, Tampa, Florida (1994) American Society for Mass Spectrometry Conference, Chicago, Illinois (1994)
• Worked as a judge at the “Feria Cientifica Nacional”, Caguas, Puerto Rico (1992)
• Professional Advisor for Administracion de Servicios Empleados Municipales (1998 to date) Advisor for the “Federación de Baloncesto” (1999)
• Delegate from the School of Pharmacy, University of Puerto Rico to the American Association of Colleges of Pharmacy Interim Meeting (1999)
• Member, Special Committee “Planificación y Desarrollo Institucional del Recinto de Ciencias Médicas: Meta 5” subcommittee, University of Puerto Rico, Medical Sciences Campus
• Member, Special Committee “Committee Ana 2000”, University of Puerto Rico, Medical Sciences Campus Lecturer, School of Medicine, University of Puerto Rico Judge, “Feria Científica Distrito Escolar de Caguas y a nivel Nacional”, Caguas Puerto Rico (1995 to date)
• Interviewer, Admission Committee, School of Pharmacy, University of Puerto Rico (1995 to date)
• Coordinator, Workshop “Introducción de Internet para Profesional de la Salud”, School of Pharmacy, University of Puerto Rico (1997)
• Member, Biosafety Committee, University of Puerto Rico, Medical Sciences Campus (2000-present)
• Professional Advisor for Rabel Law Firm (1998 to date)
• Lecturer, School of Public Health Graduate Program (1997, 1998, 2003)
• Advisor for FDA in Pharmaceutical Science (2000-2004)
• Advisor Ad Honorem for the Public Ministry of Guatemala (2000)
• Advisory Committee for Pharmaceutical Science (2000)
• Advisory Committee for Process Analytical Technology for FDA (2002)
• Advisor in Drug Analysis for the Forensics Sciences Institute (2002)
• Advisor Ad Honorem for the Universidad del Valle, Guatemala (2004)
• Advisor for the Laboratorio Nacional de Guatemala, Guatemala (2005)
• Advisor for Universidad Autónoma de Campeche (2004)
Attendance at Continuing Education and Professional Activities:
• Management Skills Course, Institute of Forensic Sciences, San Juan, PR (March 2007 – present)
• Personalized Health and Drug Safety: The Physiogenomic Prediction of Individual Response to Treatment, Universidad de Puerto Rico, Recinto de Ciencias Médicas, San Juan, Puerto Rico, January (2006)
• Proyecto Atlantea 8va Jornada de Estudios Caribeños, Universidad de Puerto Rico, Recinto de Río Piedras, March 2006
• Comité Institucional Leyes Federales “American with Disabilities Act” (ADA) y “Rehabilitation Act”, Universidad de Puerto Rico, Recinto de Ciencias Médicas, San Juan, Puerto Rico, November (2005)
• Técnicas de Microscopía y Espectroscopia de Superficie: Caracterización de Materiales, 64ta Conferencia y Convención Anual del Colegio de Químicos, August (2005)
• Mass Spectrometry as Tool in the QA/QC Laboratory, Universidad de Puerto Rico, Recinto de Ciencias Médicas, San Juan, Puerto Rico, August (2005)
• Understanding and Solving HPLC Problems, Universidad de Puerto Rico, Recinto de Ciencias Médicas, San Juan, Puerto Rico, August (2005)
• Analytical Method Validation, Universidad de Puerto Rico, Recinto de Ciencias Médicas, San Juan, Puerto Rico, August (2005)
• PAT Process Analytical Technology Intermediate Workshop, Universidad de Puerto Rico, Recinto de Ciencias Médicas, San Juan, Puerto Rico, August (2005)
• Taller de Ley HIPAA para Investigadores, Universidad de Puerto Rico, Recinto de Ciencias Médicas, San Juan, Puerto Rico, August (2005)
• De la Pre-clínica a la Clínica: Uso de la Modelación para Calcular la Dosis de AcM h-R3 en Ensayos Clínicos Fase I, Universidad de Puerto Rico, Recinto de Ciencias Médicas, San Juan, Puerto Rico, August (2005)
• Mass Spectrometry: A Versatile Tool for Clinical Chemistry, Universidad Metropolitana, May 2005
• Development of Liposome-Mediated Gene Delivery in Brain, Universidad de Puerto Rico, Recinto de Ciencias Médicas, May 2005
• El Registro de Notas en Excel, Universidad de Puerto Rico, Recinto de Ciencias Médicas, May 2005
• Natural Products and Potencial Biomedical Uses, Universidad de Puerto Rico, Recinto de Ciencias Médicas, May 2005
• Mientras más Enseño Menos Aprenden, Universidad de Puerto Rico, Recinto de Ciencias Médicas, January 2005.
• Use of Herbs and Herbal Products by Hispanics in South Florida, Universidad de Puerto Rico, Recinto de Ciencias Médicas, San Juan, Puerto Rico, December (2004)
• Strategies for Preparing Successful Research Grant Applications, University of Puerto Rico, Public Health School, October 2004.
• Tips for Proposal Writing, Universidad de Puerto Rico, Recinto de Ciencias Médicas, October 2004.
• “Current Concepts and Techniques for Protein Biomarker Discovery and Identification” Workshop, University of Puerto Rico, Medical Sciences Campus, San Juan, Puerto Rico, September 2004.
• Intercambiabilidad Terapéutica – Estudios de Biodisponibilidad y Bioequivalencia, Dr. Néstor Pérez Souto, VII Asamblea General de la Conferencia Hispanoamericana de Facultades de Farmacia, Ciudad de Guatemala, Guatemala, Abril (2004)
• Avances de la Unificación Aduanera en Centroamérica, Dra. Carmen Giral Barnés, VII Asamblea General de la Conferencia Hispanoamericana de Facultades de Farmacia, Ciudad de Guatemala, Guatemala, Abril (2004)
• La creatividad del Docente en Ciencias Farmacéuticas, Faustina Aragón, VII Asamblea General de la Conferencia Hispanoamericana de Facultades de Farmacia, Ciudad de Guatemala, Guatemala, Abril (2004)
Membership in Honorary and Professional Societies:
• American Society for Mass Spectrometry American Chemical Society
• American Association of College of Pharmacy
• International Who’s Who Association
• American Association for the Advancement of Science
• Advisory Committee for Pharmaceutical Science (FDA)
• American Chemical Society
Other activities:
• Member of an advisory committee of the FDA at the National level. Important decisions are made for different standard operating procedures, pharmaceutical studies and public politics in relation to drugs and their analysis.(1999-2003)
• Counselor for different organizations in drug related matters (Forensic Sciences Institute, Public Ministry of Guatemala, FDA San Juan District) such as analysis of samples, procedures for collection of samples, chain of custody, interpretation of results, and others. Served as a witness in administrative and public hearings. (2000-present)
• Consultant for various Law Firms in drug related matters such as sample collection, sample preparation, interpretation of results, etc. Served as a witness in hearings related to the cases. (Since 1998)
• Member of the “Comité de Planificación Estratégica del Recinto de Ciencias Médicas” in the subcommittee for strategic planning to communicate, reveal or spread information utilizing the latest technology (2001)
• Developed the Chemical Analysis Laboratory used by the Olympic Committee during the ‘XVII Juegos Centroamericanos y del Caribe”, “Juegos Nacionales de Colombia”, “Juegos Suramericanos en Venezuela”, “Administración del Deporte Hípico”, “Departamento de Educación. (1993-1998)
Publications:
• Bloom, J., Ortiz, J., Rodriguez, J.F., Azidothymidine Triphosphate Determination Using Micellar Electrokinetic Capillary Chromatography, Cell and Molec. Biol. 43(7), 1051 (1997)
• Bloom, J., Lehman, P., Israel, M., Rosario, O. and Korfmacher, WA., Mass Spectral Characterization of Three Anthracycline Antibiotics: A Comparison of Thermospray Mass Spectrometry to Particle Beam Mass Spectrometry, J. Anal. Toxicol, 16(4), 223 (1992)
• Korfmacher, WA., Freeman, J.P., Getek, T.A., Bloom, J. and Holder, C.L., Analysis of Rat Urine for Metabolites of Pyrilamine via High-Performance Liquid Chromatography/Thermospray and Tandem Mass Spectrometry, Biomed. Environ. Mass Spectrom, 19 (1991)
• Korfmacher, W.A., Chiarelli, M.P., Lay, J.O. Jr., Bloom, J., Holcomb, M. and McManus, K T., Characterization of the Mycotoxin Fumonisin B 1: Comparison of Thermospray, Fast-atom Bombardment and Electrospray Mass Spectrometry, Rapid Commun. Mass Spectrom., 5, 463 (1991)
• Korfmacher, W.A., Getek, T.A., Hansen, E.B. and Bloom, J., Characterization of Diphenhydramine, Doxylimine and Carbinoxamine Using High Performance Liquid Chromatogaphy/Thermospray Mass Spectrometry, LC-GC 8, 538 (1990)
Presentations:
• Bloom, J., Desarrollo y Validación de Metodología Analítica para Establecer Protocolos de Suplementos Dietéticos, Proyecto Atlantea 8va Jornada de Estudios Caribeños, Universidad de Puerto Rico, Recinto de Río Piedras, March 2006
• López, V. Bloom, J., Vega, J., Moreno, J, Melatonin Analysis in Dietary Supplements by HPLC using UV-Vis Detector, XXVI Foro Anual de Investigación y Educación, University of Puerto Rico, Medical Sciences Campus, April (2006)
• Bloom, J., López, J.A., Negrón, I., Cruz, R., Analysis of a Generic Ear Drops Complaint Sample by HPLC-UV and GC/MS, I Congreso Internacional de Química Analítica Aplicada, Universidad Norbert Weiner, Lima, Perú, Octubre 2005
• Bloom, J., Gonzalez, M.C. Proyecto Investigativo sobre la Prevención en el Campo de las Deficiencias en el Desarrollo, Oficina del Procurador de las Personas con Impedimentos, San Juan, Puerto Rico, December 2004
• Bloom, J., López, J.A., Negrón, I., Cruz, R. Analysis of a Generic Ear Drops Complaint Sample by HPLC-UV and GC/MS, FDA Science Forum, Washington, DC, April 2003
• Bloom, J., The Impact of Mass Spectrometry in the Analysis of Proteomics, 1999 Seminar Series, Departments of Physiology, Biochemistry, RCMI Program, UPR-RCM, May 18, 1999
• Ramirez, R.D., Bloom, J., Rodriguez, J.F., Jimenez, B.D.,Determination and Quantitation of Environmental Organic Pollutants in Edible Fish Tissue by GC-MS Ion Trap, 2~ Annual International Symposium on Environmental Analytical Chemistry, Geneva, Switzer/and, March (1998).
• Bloom, J., Ortiz, J. Rodriguez, J.F., Azidothymidine Triphosphate Detennination Using Micellar Electrokinetic Capillary Chromatography, 18th Annual Research Forum, Medical Science Campus, University of Puerto Rico, San Juan, Puerto Rico (1997).
• Ramirez, R.D., Bloom, J., Rodriguez, J.F., Jimenez, B.D., Environmental Organic Pollutants in Aquatic Animal Tissues from a Contaminated Caribbean Estuary Lagoon, SETAC 18h Annual Meeting, November 1997, San Francisco, California.
• Marrero-Ortiz, R., Bloom, J., Rodriguez, J.F., Jimenez, B.D.,Rodríguez, C.J., Environmental Organic Pollutants in Aquatic Animal Tissues from a Contaminated Caribbean Estuary Lagoon, SETAC 1~ Annual Meeting, November 1997, San Francisco, California.
• W. T., Monsanto, H.A, Gutierrez, LM., the Curriculum Committee, Omla, M., The Incorporation of Pharmaceutical Care as an Outcome Ability in the Development of the Conceptual Map of an Entry-
• Level Doctor of Pharmacy Program, American Association of Colleges of Pharmacy Annual Meeting, July (1997).
• Bloom, J., Ortiz, J., Rodriguez, J.F., Azidothymidine Triphosphate Characterization by Micellar Electrokinetic Capillary Chromatography, ~ International Symposium on Pharmaceutical and Biomedical Analysis, Orlando Florida, May (1997)
• Bloom, J., Ramirez, R.D, Rodriguez, J.F., Jimenez, B.D, Determination of Organic Pollutants in Fish Tissue by GCIMS Ion Trap, 5th EPSCoR Annual Meeting, Fajardo, Puerto Rico, May (1997).
• Bloom, J., Ortiz, J. Rodriguez, J.F., Method Development for the Characterization of IntracellularAZT-TPUsing Capillary Electrophoresis, s’h RCMI-NIH International AIDS Symposium, November 1996, Rio Grande, Puerto Rico.
• Rodriguez, J.F., Marti, A, Bloom, J., Alvarez, M., Monitoring Doping Control Drugs During the XVII Central American and Caribbean Games, 16th Annual Research Forum, Medical Science Campus, University of Puerto RICO, San Juan, Puerto Rico (1995)
• Bloom, J., Alvarez, M., Rodriguez, J.F. and Martí, A., A Close Look at the Use in Sports Elite Centro American Athletes, 16th Annual Research Forum, Medical Science Campus University of Puerto Rico San Juan Puerto Rico (1995) ” , Korfmacher, WA, Abian, J., Bloom, J., Churchwell,
• M.I., Utility of Thermospray HPLC/MS for the Analysis of Pharmaceuticals and Metabolites, Federation of Analytical Chemistry & Spectroscopy Societies Philadelphia, Pennsylvania (1992)
• Hansen, E.B. Jr., Bloom, J., Thompson, H.C. Jr. and Korfmacher, WA., Utility of HLPC/TSMS for the Analysis of the Antituberculosis Drugs Aconiazide and Isoniazide, at the 3gth ASMS Conference on Mass Spedrometry [f and Allied Topics, Nashville, Tennessee, p. 1344 (1991)
• Churchwell, M., Korfmacher, WA. and Bloom, J., Analysis of Sulfamethazine in Milk by Thermospray Liquid Chromtography/Mass Spectrometry, at the 31th ASMS Conference on Mass Spectrometry and Allied Topics, Nashville, Tennessee, p. 1342 (1991)
• Korfmacher, WA, Bloom, J., Chiarelli, P., Lay, J.O. Jr., Holcomb, M. and McManus, K. T, Comparison of Thermospray, FAB, and E/ectrospray for the MS Characterization of the Micotoxin Fumonisin B 1, at the 31st ASMS Conference on Mass Spectrometry and Allied Topics, Nashville, Tennessee, p. 710 (1991)
• Korfmacher, WA., Bloom, J., Churchwell, M.I. and McManus, K. T., Comparison of Thermospray and Electrospray for the MS Characterization of Three Anthracyc/ines, at the 3g111 ASMS Conference on Mass Spectrometry and Allied Topics, Nashville, Tennessee, p. 595 (1991)
• Bloom, J., Korfmacher, WA, Israel, M. and Rosario, 0., Utility of HPLC/TSMS for the Analysis of Three Anthracyc/ines, at the 3gth ASMS Conference on Mass Spectrometry and Allied Topics, Nashville, Tennessee, p. 571 (1991)
• Bloom, J., Lehman, P., Korfmacher, WA., Israel, M. and Rosario, 0., EIMSandPBCIMS for the Analysis of Doxorubicin, Daunorubicin, and Canninomycin, at the 3g1h ASMS Conference on Mass Spectrometry and Allied Topics, Nashville, Tennessee, p. 569 (1991)
• Holder, C.L, Churchwell, M.I., Korfmacher, WA., Bloom, J., Billedeau, S.M., Evans, F.E., Bryant, M.S. and Stone, A., Investigation of Heterocyclic Amines and Two of The N-oxidation Products by Thermospray Mass Spectrometry, at the 31th ASMS Conference on Mass Spectrometry and Allied Topics, Nashville, Tennessee, p. 308 (1991)
• Bloom, J., Getek, T.A., Freeman, J.P., Holder, C.L and Korfmacher, WA, Applications of LC-MS and LC-MS-MS to the Analysis of Rat Urine for Pyrilamine Metabolites, at the National Symposium on Health Research Carrer Opportunities for Hispanic Americans, San Antonio, Texas (1989)
• Bloom, J., Getek, TA. and Korfmacher, WA., Utility of HPLC combined with Thermospray MS for the Analysis of Rifampicin and other related compounds, at the 3dh ASMS Conference on Mass Spectrometry and Allied Topics, Tucson, Arizona, p.1051 (1990)
• Bloom, J., Korfmacher, WA., Freeman, J.P., Getek, T.A. and Holder, C.L, Utility of LC-MS and Tandem MS for the Analysis of the Rat Urine Metabolites of Pyrilamine, at the 3″fh ASMS Conference on Mass Spectrometry and Allied Topics, Miami Beach, Florida, p. 1302 (1989)
Proposals:
• “Measuring Antiretroviral Metabolites at the Intracellular Level using Capillary Electrophoresis”, submitted to CIDIC at Medical Sciences Campus, Joseph Bloom, Jose F. Rodriguez, funded $39,000, 1995-96 and 1996-97
• “Detección Temprana de Niños con Deficiencias en el Desarrollo par Acidemias Orgánicas”, $75,000 submitted to Consejo Estatal de Deficiencias en el Desarrollo, Joseph Bloom, Maria del C. González and approved. (2002)
• “Efecto de la Ingestión de Acetaminofen-Difenhidramina en los Ensayos Inmunoenzimaticos para Cocaína”, Joseph Bloom, Estela Estapé, approved by IRB, not funded but reagents for the research were supplied by Clendo Labs. (1998)
• “Assessment of the Jobos Bay Estuarine Research Reserve”, $200,000 submitted to Sea Grant College Program and NOAA, Braulio Jiménez, Joseph Bloom, Carlos Rodríguez, Wilfredo Delgado, Jose F. Rodríguez (1998)
• “Determination of F2-isoprostanes in plasma and Cerebrospinal Fluid of HIV Infected Patients, $15,000, submitted to CRC at the Medical Sciences Campus, Joseph Bloom, Maritere García (2001)
• “Toxicological Evaluation and Chemical Composition of PM10 and PM25 Urban Particulate Matter”, submitted to Environmental Protection Agency (EPA), funded $500,000 from 1999-2002, Braulio Jiménez, Joseph Bloom, Osvaldo Rosario, Carmen Cadilla, Guido Santacana, Carlos Rodriguez, Yashimuro Yamamura
• “Proposal to Strengthen the EPSCoR Program for Environmental Toxicological Research in Puerto Rico, submitted to EPSCoR, funded 1994 – 1996, $1,000,000, Braulio Jiménez, Joseph Bloom, Carmen González, F. Fuentes Wilfredo Delgado, Carlos Rodríguez, Jose F. Rodríguez
• “Pharmacokinetic Studies of Intracellular ZDV in Children”, RO 1 submitted to National Institute of Health (NIH) funded from 1995-2000, $1,326,688, Jose F. Rodríguez, Joseph Bloom, Clemente Díaz, Philip Specht, Wanda Maldonado, Arnold Fredland, James D. Connor, John Rodman
• “Evaluation of Heavy Metals and Biomarkers in Aquatic Organisms from the San Jose Lagoon, submitted to Sea Grant College and NOAA Program (2000)
• “Environmental Pollutants in Aquatic Organisms from the San Jose Lagoon, submitted to EPA, funded from 1998 – 2000, Braulio Jiménez, Carlos Rodríguez, Wilfredo Delgado, Jose F. Rodríguez, Joseph Bloom
• Analysis of Acylcamitines in our Neonatal Population., submitted to COPENIC and accepted $14,898 (2001)
• Major Instrumentation Proposal “Acquisition of a Tandem Mass Spectrometry Instrument to Enhanced Research Capabilities at the University of Puerto Rico Medical Sciences Campus., submitted to EPSCoR, and to be submitted to NSF
• “La Tecnología de Avanzada Integrada a un Currículo por Competencias”, submitted to Administración Central, University of Puerto Rico and accepted $41,950.00 (2001)
• Proyecto Atlantea “Desarrollo y Validación de Metodología Analítica para Establecer Protocolos de Suplementos Dietéticos”, Premio al mejor diseño de Proyecto Individual. $14,550.00
Courses Taught and Developed:
FARM 4006 Drug Analysis 3 credits; 36 contact hours (undergraduate)
FARM 4006L Drug Analysis Lab 2 sections; 72 contact hours (undergraduate)
FAQM 6351 Instrumental Pharmaceutical Analysis I 2 credits; 24 contact hours (graduate)
FAQM 6352 Instrumental Pharmaceutical Analysis 11 2 credits; 24 contact hours (graduate)
FAGG 6300 Principles of Research Design 2 credits: (graduate)
FAGG 6800 MS Research 2 credits/student (2×3 students) 72 contact hours/student
(144 contact hours per trimester) (graduate)
FARM 6213 Mass Spectrometry in Drug Analysis 2 credits; 24 contact hours (graduate)
FARM 4288 Pharmaceutical Analysis Techniques 2 credits; 36 contact hours (undergraduate)
FARM 6312 Seminar in Medicinal Chemistry 2 credits; 24 contact hours (graduate)
FARM 6200 Drug Literature Evaluation 2 credits; 24 contact hours (graduate)
FARM 4277 Undergraduate Research 5 credits; 180 contact hours (undergraduate)
CILC 6017 Advanced Studies in Clinical Biochemistry I 2 credits; 24 contact hours (undergraduate)
CILC 6115 Practice in Clinical Biochemistry 2 credits; 24 contact hours (graduate)
SAAM 6535 Toxicología Ambiental 2 credits; 24 contact hours (graduate)
SAAM 8010 Análisis Instrumental 2 credits; 24 contact hours (graduate)
Training:
• Training in Radiation Safety, University of Puerto Rico, Medical Sciences Campus, February 28, 2005
• Training in the Application of Tandem Mass Spectrometry and the Production and Certification of Dried-Blood Spot Quality Materials, Center for Disease Control, May 2003
• Training on Perkin-Elmer GC/MS drug analysis and data handling, April 23, 2002
• The National Library of Medicine’s Toxicology and Environmental Health Databases, University of Puerto Rico, School of Medicine, San Juan Puerto Rico, April 2-3, 2001
• Fundamentals of Dissolution, Advanced Instruments, April 2001
• Training on “Exposición Ocupacional a Patógenos Transmitidos por la Sangre”, May 5, 1999,
sponsored by UPR-RCM
• Introduction to Excel ’95, May 20, 1998, sponsored by UPR-RCM
• GC/MS Workshop, May 7, 1998, sponsored by Advanced Instruments LCIMS Workshop, May 8, 1998, sponsored by Advanced Instruments
• GCQ Mass Spectrometry Training Course, February 9-13, 1998. Training on the use of GC/MS and MS/MS on a GCQ Ion Trap MS/MS instrument. This included tuning, calibration, data handling, and troubleshooting. This training was sponsored by Finnigan ThermoQuest
• Training Course Using the Online Toxicology and Environmental Health Information Program Files of the National Library of Medicine, July 3D-August 1, 1197, sponsored by Oak Ridge Institute for Science and Education
• Introduction to Windows ’95, January 9, 1997, sponsored by UPR-RCM
• Capillary Electrophoresis, July 1-12, 1996. Training on the capillary electrophoresis technique and instrumentation at the National Cancer Institute. Training include the use of instrumentation, troubleshooting, and analysis of AZT by capillary electrophoresis, use of different types of buffer system, and creating and developing my own capillary columns. This was sponsored by an RCMI Travel Award
• Quattro Operating Mass Spectrometry Training Course, May 6-10, 1996. Training on the use of a Quattro mass spectrometer with MS/MS capabilities, atmospheric pressure ionization, mass calibration, quantization, and various mass spectrometry modes of operation. This included applications and hands-on experience. This training was sponsored by VG Organic
• Trained in the use of a Bio-Rad CE instrument, sponsored by Bio-Rad Laboratories, April 4, 1996 GCIMS Methods in Drug Testing International Olympic Committee banned drugs analysis by GCIMS from UCLA. Trained to analyze several types of drugs used by athletes during competition which are banned by the IOC. This included from preparation of samples to the interpretation of results.
Instrumental experience:
Experienced in the use of HPLC with thermospray mass spectrometry interface on both a Finnigan MAT TSQ-70MSlMS and Delsi Nermag R-1010-C. Other mass spectrometric systems include HPLC with particle beam mass spectrometry with a Hewlett-Packard 59980A, HPLC with electrospray ionization and atmospheric pressure mass spectrometry, desorption chemical ionization with a GCIMS Finnigan 400012, Hewlett Packard GC/MS 5971with an RTE-A computer system, Fast Atom Bombardment with a Finnigan MAT TSQ-70 and on a Delsi Nermag R-3010. In addition, gas chromatography with mass spectrometry on a Hewlett-Packard 5987 A, and 5980A with an RTE-A computer system, GCIMS Ion Trap, and HPLCI/MS/MS on a Quattro instrument. Experienced in GCIMS using Helwett Packard, Finnigan MAT, PerKin Elmer and Varian instruments using various modes of detection; HPLC using Hewlett Packard, Waters, Shimadzu and Perkin Elmer equipment with several modes of detection as well. Experience in Capillary Electrophoresis with UV and LlF (Laser Induced Fluorescence), Automatic Vankel Dissolution Bath. Other methods of detection include a Waters 440 UV/Vis detector, a Waters 6880 gradient controller, an ISCO CV4 capillary electrophoresis UV detector, a Hewlett-Packard 1040A photodiode array detector, and a Shimadzu RF-535 fluorescence detector. Also experienced in associated liquid chromatographic systems and flash photolysis equipment.