Associate Professor of Toxicology
and the Marlene L. Cohen and Jerome H. Fleisch Scholar
in the Department of Pharmaceutical Sciences at the School of Pharmacy of the University of Connecticut.
Dr. José E. Manautou is Associate Professor of Toxicology and the Marlene L. Cohen and Jerome H. Fleisch Scholar in the Department of Pharmaceutical Sciences at the School of Pharmacy of the University of Connecticut. His research emphasizes mechanisms of toxicant action/interaction. His laboratory studies the role of multidrug resistance proteins in the hepatobiliary disposition of toxicants and the changes in expression of transport proteins in response to chemical liver injury. His group also investigates the biochemical and genetic determinants associated with the hepatoprotective actions of peroxisome proliferators and other chemicals that prevent drug liver injury.
He has published numerous seminal articles on these research areas in both toxicology and liver-related journals. Dr. Manautou has been an active member of the Society of Toxicology (SOT) since he joined as a student member. In 2003, he was elected Councilor of the SOT and has also served in key committees and task forces for the society. Dr. Manautou was the recipient of the 2006 SOT Achievement Award and the 2008 AstraZeneca Traveling Lectureship Award. Dr. Manautou has served as member of the National Research Council Committee Assessing the Human Health Risks of Trichloroethylene and is currently Associate Editor for the journal Toxicology and Applied Pharmacology.
He is also on the editorial board of four other journals. He served as member of the National Institutes of Health Xenobiotic and Nutrient Disposition and Action (XNDA) Study Section and as external reviewer of grants for the European Commission. Dr. Manautou was recently appointed the NIH College of CSR Reviewers and was just nominated to be a member of the NIEHS Board of Scientific Counselors. Dr. Manautou received his B.S. in Pharmacy from the University of Puerto Rico, Ph.D. in Pharmacology and Toxicology from Purdue University and postdoctoral training in biochemical toxicology at the University of Connecticut. He also conducted sabbatical research at the Amsterdam Liver Center of the University of Amsterdam, The Netherlands.